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Salt Tolerance Enhancement of Liquid Chromatography-Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Using Matrix Additive Methylenediphosphonic Acid

Mass spectrometry (MS) is a highly sensitive analytical technique that is often coupled with liquid chromatography (LC). However, some buffering salts used in LC (e.g., phosphate and tris(hydroxymethyl)aminomethane (Tris)) are incompatible with MS since they cause ion-source contamination and signal...

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Dettagli Bibliografici
Pubblicato in:Mass Spectrom (Tokyo)
Autori principali: Ohta, Yuki, Iwamoto, Shinichi, Kawabata, Shin-ichirou, Tanimura, Ritsuko, Tanaka, Koichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Mass Spectrometry Society of Japan 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306744/
https://ncbi.nlm.nih.gov/pubmed/26819873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5702/massspectrometry.A0031
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