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Salt Tolerance Enhancement of Liquid Chromatography-Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Using Matrix Additive Methylenediphosphonic Acid

Mass spectrometry (MS) is a highly sensitive analytical technique that is often coupled with liquid chromatography (LC). However, some buffering salts used in LC (e.g., phosphate and tris(hydroxymethyl)aminomethane (Tris)) are incompatible with MS since they cause ion-source contamination and signal...

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Detalhes bibliográficos
Publicado no:Mass Spectrom (Tokyo)
Main Authors: Ohta, Yuki, Iwamoto, Shinichi, Kawabata, Shin-ichirou, Tanimura, Ritsuko, Tanaka, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: The Mass Spectrometry Society of Japan 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306744/
https://ncbi.nlm.nih.gov/pubmed/26819873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5702/massspectrometry.A0031
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