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Hepatic oleate regulates adipose tissue lipogenesis and fatty acid oxidation
Hepatic steatosis is associated with detrimental metabolic phenotypes including enhanced risk for diabetes. Stearoyl-CoA desaturases (SCDs) catalyze the synthesis of MUFAs. In mice, genetic ablation of SCDs reduces hepatic de novo lipogenesis (DNL) and protects against diet-induced hepatic steatosis...
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| Published in: | J Lipid Res |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Biochemistry and Molecular Biology
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4306685/ https://ncbi.nlm.nih.gov/pubmed/25555387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M054429 |
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