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Acidification of the intimal fluid: the perfect storm for atherogenesis

Atherosclerotic lesions are often hypoxic and exhibit elevated lactate concentrations and local acidification of the extracellular fluids. The acidification may be a consequence of the abundant accumulation of lipid-scavenging macrophages in the lesions. Activated macrophages have a very high energy...

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Bibliografski detalji
Izdano u:J Lipid Res
Glavni autori: Öörni, Katariina, Rajamäki, Kristiina, Nguyen, Su Duy, Lähdesmäki, Katariina, Plihtari, Riia, Lee-Rueckert, Miriam, Kovanen, Petri T.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306676/
https://ncbi.nlm.nih.gov/pubmed/25424004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R050252
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