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Structural and Functional Studies of the Potent Anti-HIV Chemokine Variant P2-RANTES

The N-terminal region of the chemokine RANTES is critical for its function. A synthesized N-terminally modified analog of RANTES, P2-RANTES, was discovered using a phage display selection against living CCR5-expressing cells, and has been reported to inhibit HIV-1 env-mediated cell-cell fusion at su...

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Bibliografiske detaljer
Udgivet i:Proteins
Main Authors: Jin, Hongjun, Kagiampakis, Ioannis, Li, Pingwei, LiWang, Patricia J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306592/
https://ncbi.nlm.nih.gov/pubmed/19722264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22542
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