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Structural and Functional Studies of the Potent Anti-HIV Chemokine Variant P2-RANTES
The N-terminal region of the chemokine RANTES is critical for its function. A synthesized N-terminally modified analog of RANTES, P2-RANTES, was discovered using a phage display selection against living CCR5-expressing cells, and has been reported to inhibit HIV-1 env-mediated cell-cell fusion at su...
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| Publié dans: | Proteins |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4306592/ https://ncbi.nlm.nih.gov/pubmed/19722264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22542 |
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