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ALTERED INTERACTIONS BETWEEN CARDIAC MYOSIN BINDING PROTEIN-C AND α-CARDIAC ACTIN VARIANTS ASSOCIATED WITH CARDIOMYOPATHIES

The two genes most commonly associated with mutations linked to hypertrophic or dilated cardiomyopathies are β-myosin and cardiac myosin binding protein-C (cMyBP-C). Both of these proteins interact with cardiac actin (ACTC). Currently there are 16 ACTC variants that have been found in patients with...

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Pubblicato in:Arch Biochem Biophys
Autori principali: Chow, Melissa L., Shaffer, Justin F., Harris, Samantha P., Dawson, John F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306385/
https://ncbi.nlm.nih.gov/pubmed/24736382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2014.04.003
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