BKCa channel inhibitor modulates the tumorigenic ability of hormone-independent breast cancer cells via the Wnt pathway

In breast cancers, the large conductance Ca(2+) and voltage sensitive K(+) (BKCa) channels have been hypothesized to function as oncoproteins, yet it remains unclear how inhibition of channel activity impacts oncogenesis. We demonstrated herein that iberiotoxin (IbTX), an inhibitor of BKCa channels,...

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發表在:Oncol Rep
Main Authors: SCHICKLING, BRANDON M., ENGLAND, SARAH K., AYKIN-BURNS, NUKHET, NORIAN, LYSE A., LESLIE, KIMBERLY K., FRIEDEN-KOROVKINA, VICTORIA P.
格式: Artigo
語言:Inglês
出版: D.A. Spandidos 2015
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306270/
https://ncbi.nlm.nih.gov/pubmed/25422049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2014.3617
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