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Localization of low density lipoprotein receptors on plasma membrane of normal human fibroblasts and their absence in cells from a familial hypercholesterolemia homozygote.

Monolayers of normal human fibroblasts were observed to bind ferritin-labeled low density lipoprotein (LDL-ferritin) at specific receptor sites on the cell surface membrane. When fibroblasts were incubated with LDL-ferritin at 4 degrees, more than 70% of the surface-bound ferritin cores were localiz...

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Bibliografiske detaljer
Main Authors: Anderson, R G, Goldstein, J L, Brown, M S
Format: Artigo
Sprog:Inglês
Udgivet: 1976
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC430596/
https://ncbi.nlm.nih.gov/pubmed/181751
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