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Treatment-related Hypertension as a Pharmacodynamic Biomarker for the Efficacy of Bevacizumab in Advanced Pancreas Cancer: A Pooled Analysis of 4 Prospective Trials of Gemcitabine-based Therapy With Bevacizumab
PURPOSE: Phase III studies of bevacizumab in advanced pancreas cancer (APCA) demonstrated no improvement in outcome. No validated biomarkers for bevacizumab efficacy exist. We evaluated bevacizumab-related hypertension (B-HTN) as a biomarker in APCA patients in a pooled analysis from 4 prospective c...
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發表在: | Am J Clin Oncol |
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Main Authors: | , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
2016
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4305484/ https://ncbi.nlm.nih.gov/pubmed/25068471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COC.0000000000000108 |
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