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A Pathway-Centric Survey of Somatic Mutations in Chinese Patients with Colorectal Carcinomas

Previous genetic studies on colorectal carcinomas (CRC) have identified multiple somatic mutations in four candidate pathways (TGF-β, Wnt, P53 and RTK-RAS pathways) on populations of European ancestry. However, it is under-studied whether other populations harbor different sets of hot-spot somatic m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ling, Chao, Wang, Lin, Wang, Zheng, Xu, Luming, Sun, Lifang, Yang, Hui, Li, Wei-Dong, Wang, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305320/
https://ncbi.nlm.nih.gov/pubmed/25617745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116753
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