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Somatic mutation profiling and HER2 status in KRAS-positive Chinese colorectal cancer patients
KRAS is an independent negative predictor for anti-epidermal growth factor receptor (anti-EGFR) treatment in colorectal cancers (CRCs). However, 30% to 50% of CRC patients are KRAS-positive and do not benefit from anti-EGFR therapy. In this study, we investigated the mutational features and clinical...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6858340/ https://ncbi.nlm.nih.gov/pubmed/31729406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53039-y |
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