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Probing Conformational Stability and Dynamics of Erythroid and Nonerythroid Spectrin: Effects of Urea and Guanidine Hydrochloride

We have studied the conformational stability of the two homologous membrane skeletal proteins, the erythroid and non-erythroid spectrins, in their dimeric and tetrameric forms respectively during unfolding in the presence of urea and guanidine hydrochloride (GuHCl). Fluorescence and circular dichroi...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Patra, Malay, Mukhopadhyay, Chaitali, Chakrabarti, Abhijit
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305312/
https://ncbi.nlm.nih.gov/pubmed/25617632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116991
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