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Activation of chicken liver dihydrofolate reductase by urea and guanidine hydrochloride is accompanied by conformational change at the active site.

It has been reported that the activation of dihydrofolate reductase (DHFR) from L1210 mouse leukaemia cells by KCl or thiol modifiers is accompanied by increased digestibility by proteinases [Duffy, Beckman, Peterson, Vitols and Huennekens (1987) J. Biol. Chem. 262, 7028-7033], suggesting a loosenin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Fan, Y X, Ju, M, Zhou, J M, Tsou, C L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1996
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217202/
https://ncbi.nlm.nih.gov/pubmed/8670138
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