The many weak instruments problem and Mendelian randomization

Instrumental variable estimates of causal effects can be biased when using many instruments that are only weakly associated with the exposure. We describe several techniques to reduce this bias and estimate corrected standard errors. We present our findings using a simulation study and an empirical...

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Bibliografiske detaljer
Udgivet i:Stat Med
Main Authors: Davies, Neil M, von Hinke Kessler Scholder, Stephanie, Farbmacher, Helmut, Burgess, Stephen, Windmeijer, Frank, Smith, George Davey
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305205/
https://ncbi.nlm.nih.gov/pubmed/25382280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6358
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