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The many weak instruments problem and Mendelian randomization

Instrumental variable estimates of causal effects can be biased when using many instruments that are only weakly associated with the exposure. We describe several techniques to reduce this bias and estimate corrected standard errors. We present our findings using a simulation study and an empirical...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Davies, Neil M, von Hinke Kessler Scholder, Stephanie, Farbmacher, Helmut, Burgess, Stephen, Windmeijer, Frank, Smith, George Davey
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305205/
https://ncbi.nlm.nih.gov/pubmed/25382280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6358
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