Human Mannose-Binding Lectin Inhibitor Prevents Myocardial Injury and Arterial Thrombogenesis in a Novel Animal Model

Myocardial infarction and coagulation disorders are leading causes of disability and death in the world. An important role of the lectin complement pathway in myocardial infarction and coagulation has been demonstrated in mice genetically deficient in lectin complement pathway proteins. However, the...

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Veröffentlicht in:Am J Pathol
Hauptverfasser: Pavlov, Vasile I., Tan, Ying S., McClure, Erin E., La Bonte, Laura R., Zou, Chenhui, Gorsuch, William B., Stahl, Gregory L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2015
Schlagworte:
Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305178/
https://ncbi.nlm.nih.gov/pubmed/25482922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.10.015
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