Human mannose-binding lectin inhibitor prevents Shiga toxin-induced renal injury

Hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli (STEC HUS) is a worldwide endemic problem and its pathophysiology is not fully elucidated. Here we tested whether the mannose-binding lectin (MBL2), an initiating factor of lectin complement pathway activation, plays a crucia...

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Pubblicato in:Kidney Int
Autori principali: Ozaki, Masayuki, Kang, Yulin, Tan, Ying Siow, Pavlov, Vasile I., Liu, Bohan, Boyle, Daniel C., Kushak, Rafail I., Skjoedt, Mikkel-Ole, Grabowski, Eric F., Taira, Yasuhiko, Stahl, Gregory L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026569/
https://ncbi.nlm.nih.gov/pubmed/27378476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.05.011
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