Alectinib Salvages CNS Relapses in ALK-Positive Lung Cancer Patients Previously Treated with Crizotinib and Ceritinib

BACKGROUND: Leptomeningeal metastases (LM) are an increasingly frequent and devastating complication of anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC). Currently, the optimal management of LM in ALK-positive patients remains poorly understood as these patients have be...

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Pubblicato in:J Thorac Oncol
Autori principali: Gainor, Justin F., Sherman, Carol A., Willoughby, Kathryn, Logan, Jennifer, Kennedy, Elizabeth, Brastianos, Priscilla K., Chi, Andrew S., Shaw, Alice T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304931/
https://ncbi.nlm.nih.gov/pubmed/25526238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000455
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