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Molecular controls of lymphatic VEGFR3 signaling

OBJECTIVES: Vascular endothelial growth factor receptor 3 (VEGFR3) plays important roles both in lymphangiogenesis and angiogenesis. Upon stimulation by its ligand VEGF-C, VEGFR3 is able to form both homodimers as well as heterodimers with VEGFR2 and activates several downstream signal pathways incl...

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Bibliographische Detailangaben
Veröffentlicht in:Arterioscler Thromb Vasc Biol
Hauptverfasser: Deng, Yong, Zhang, Xi, Simons, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304921/
https://ncbi.nlm.nih.gov/pubmed/25524775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304881
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