Sustained virological response with intravenous silibinin: individualized IFN-free therapy via real-time modeling of HCV kinetics

BACKGROUND & AIMS: Intravenous silibinin (SIL) is a potent antiviral agent against hepatitis C virus (HCV) genotype-1. In this proof of concept case-study we tested: (i) whether interferon-alfa (IFN)-free treatment with SIL plus ribavirin (RBV) can achieve sustained virological response (SVR), (...

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Detalhes bibliográficos
Publicado no:Liver Int
Main Authors: Dahari, Harel, Shteingart, Shimon, Gafanovich, Inna, Cotler, Scott J., D'Amato, Massimo, Pohl, Ralf T., Weiss, Gali, Ashkenazi, Yaakov Jack, Tichler, Thomas, Goldin, Eran, Lurie, Yoav
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304917/
https://ncbi.nlm.nih.gov/pubmed/25251042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12692
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