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Basolateral EGF receptor sorting regulated by functionally distinct mechanisms in renal epithelial cells

Proliferation of epithelial tissues is controlled by polarized distribution of signaling receptors including the EGF receptor (EGFR). In kidney, EGFRs are segregated from soluble ligands present in apical fluid of nephrons by selective targeting to basolateral membranes. We have shown previously tha...

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Bibliographic Details
Published in:Traffic
Main Authors: Cotton, Calvin U., Hobert, Michael E., Ryan, Sean, Carlin, Cathleen R.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304763/
https://ncbi.nlm.nih.gov/pubmed/23205726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12032
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