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Basolateral EGF receptor sorting regulated by functionally distinct mechanisms in renal epithelial cells

Proliferation of epithelial tissues is controlled by polarized distribution of signaling receptors including the EGF receptor (EGFR). In kidney, EGFRs are segregated from soluble ligands present in apical fluid of nephrons by selective targeting to basolateral membranes. We have shown previously tha...

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Veröffentlicht in:Traffic
Hauptverfasser: Cotton, Calvin U., Hobert, Michael E., Ryan, Sean, Carlin, Cathleen R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304763/
https://ncbi.nlm.nih.gov/pubmed/23205726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12032
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