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YME1L degradation reduces mitochondrial proteolytic capacity during oxidative stress
Mitochondrial proteostasis is maintained by a network of ATP-dependent quality control proteases including the inner membrane protease YME1L. Here, we show that YME1L is a stress-sensitive mitochondrial protease that is rapidly degraded in response to acute oxidative stress. This degradation require...
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Publicado no: | EMBO Rep |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BlackWell Publishing Ltd
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4304733/ https://ncbi.nlm.nih.gov/pubmed/25433032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201438976 |
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