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YME1L degradation reduces mitochondrial proteolytic capacity during oxidative stress

Mitochondrial proteostasis is maintained by a network of ATP-dependent quality control proteases including the inner membrane protease YME1L. Here, we show that YME1L is a stress-sensitive mitochondrial protease that is rapidly degraded in response to acute oxidative stress. This degradation require...

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Bibliografski detalji
Izdano u:EMBO Rep
Glavni autori: Rainbolt, T Kelly, Saunders, Jaclyn M, Wiseman, R Luke
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304733/
https://ncbi.nlm.nih.gov/pubmed/25433032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201438976
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