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Coupling mRNA processing with transcription in time and space

Maturation of mRNA precursors often occurs simultaneously with their synthesis by RNA polymerase II (Pol II). The co-transcriptional nature of mRNA processing has permitted the evolution of coupling mechanisms that coordinate transcription with mRNA capping, splicing, editing and 3′ end formation. R...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Rev Genet
1. Verfasser: Bentley, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304646/
https://ncbi.nlm.nih.gov/pubmed/24514444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3662
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