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Protein tyrosine phosphatase receptor type R is required for Purkinje cell responsiveness in cerebellar long-term depression

BACKGROUND: Regulation of synaptic connectivity, including long-term depression (LTD), allows proper tuning of cellular signalling processes within brain circuitry. In the cerebellum, a key centre for motor coordination, a positive feedback loop that includes mitogen-activated protein kinases (MAPKs...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Erkens, Mirthe, Tanaka-Yamamoto, Keiko, Cheron, Guy, Márquez-Ruiz, Javier, Prigogine, Cynthia, Schepens, Jan TG, Nadif Kasri, Nael, Augustine, George J, Hendriks, Wiljan JAJ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304614/
https://ncbi.nlm.nih.gov/pubmed/25571783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-014-0092-8
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