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Deubiquitinases and the new therapeutic opportunities offered to cancer
Deubiquitinases (DUBs) play important roles and therefore are potential drug targets in various diseases including cancer and neurodegeneration. In this review, we recapitulate structure–function studies of the most studied DUBs including USP7, USP22, CYLD, UCHL1, BAP1, A20, as well as ataxin 3 and...
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| Veröffentlicht in: | Endocr Relat Cancer |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Bioscientifica Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4304536/ https://ncbi.nlm.nih.gov/pubmed/25605410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-14-0516 |
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