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Deubiquitinases and the new therapeutic opportunities offered to cancer

Deubiquitinases (DUBs) play important roles and therefore are potential drug targets in various diseases including cancer and neurodegeneration. In this review, we recapitulate structure–function studies of the most studied DUBs including USP7, USP22, CYLD, UCHL1, BAP1, A20, as well as ataxin 3 and...

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Podrobná bibliografie
Vydáno v:Endocr Relat Cancer
Hlavní autoři: Pfoh, Roland, Lacdao, Ira Kay, Saridakis, Vivian
Médium: Artigo
Jazyk:Inglês
Vydáno: Bioscientifica Ltd 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304536/
https://ncbi.nlm.nih.gov/pubmed/25605410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-14-0516
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