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U0126 Protects Cells against Oxidative Stress Independent of Its Function as a MEK Inhibitor

[Image: see text] U0126 is a potent and selective inhibitor of MEK1 and MEK2 kinases. It has been widely used as an inhibitor for the Ras/Raf/MEK/ERK signaling pathway with over 5000 references on the NCBI PubMed database. In particular, U0126 has been used in a number of studies to show that inhibi...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Ong, Qunxiang, Guo, Shunling, Zhang, Kai, Cui, Bianxiao
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304487/
https://ncbi.nlm.nih.gov/pubmed/25544156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500288n
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