Anticancer activity and SAR studies of substituted 1,4-naphthoquinones

In this paper, we report the structure–activity relationship studies of substituted 1,4-naphthoquinones for its anticancer properties. 1,4-Naphthoquinone, Juglone, Menadione, Plumbagin and LLL12.1 were used as lead molecules to design PD compounds. Most of the PD compounds showed improved antiprolif...

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Publicado en:Bioorg Med Chem
Autores principales: Bhasin, Deepak, Chettiar, Somsundaram N., Etter, Jonathan P., Mok, May, Li, Pui-Kai
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304211/
https://ncbi.nlm.nih.gov/pubmed/23791367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.05.017
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