Synthesis, Leishmanicidal Activity and Theoretical Evaluations of a Series of Substituted bis-2-Hydroxy-1,4-Naphthoquinones

A series of eight substituted bis-2-hydroxy-1,4-naphthoquinone derivatives was synthesized through lawsone condensation with various aromatic and aliphatic aldehydes under mild acidic conditions. The title compounds were evaluated for antileishmanial activity in vitro against Leishmania amazonensis...

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Publié dans:Molecules
Auteurs principaux: de Araújo, Morgana V., de Souza, Patricia S. O., de Queiroz, Aline C., da Matta, Carolina B. B., Leite, Anderson Brandão, da Silva, Amanda Evelyn, de França, José A. A., Silva, Tania M. S., Camara, Celso A., Alexandre-Moreira, Magna S.
Format: Artigo
Langue:Inglês
Publié: MDPI 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271274/
https://ncbi.nlm.nih.gov/pubmed/25247686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules190915180
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