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Protein sector analysis for the clustering of disease-associated mutations

BACKGROUND: The importance of mutations in disease phenotype has been studied, with information available in databases such as OMIM. However, it remains a research challenge for the possibility of clustering amino acid residues based on an underlying interaction, such as co-evolution, to understand...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Guevara-Coto, Jose, Schwartz, Charles E, Wang, Liangjiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304181/
https://ncbi.nlm.nih.gov/pubmed/25559331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-S11-S4
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