BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma

Follicular lymphoma (FL), an indolent neoplasm caused by a t(14;18) chromosomal translocation that juxtaposes the BCL2 gene and immunoglobulin locus, has a variable clinical course and frequently undergoes transformation to an aggressive lymphoma. Although BCL2 mutations have been previously describ...

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Publicat a:Blood
Autors principals: Correia, Cristina, Schneider, Paula A., Dai, Haiming, Dogan, Ahmet, Maurer, Matthew J., Church, Amy K., Novak, Anne J., Feldman, Andrew L., Wu, Xiaosheng, Ding, Husheng, Meng, X. Wei, Cerhan, James R., Slager, Susan L., Macon, William R., Habermann, Thomas M., Karp, Judith E., Gore, Steven D., Kay, Neil E., Jelinek, Diane F., Witzig, Thomas E., Nowakowski, Grzegorz S., Kaufmann, Scott H.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2015
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304111/
https://ncbi.nlm.nih.gov/pubmed/25452615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-571786
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