The hidden genomic landscape of acute myeloid leukemia: subclonal structure revealed by undetected mutations

The analyses carried out using 2 different bioinformatics pipelines (SomaticSniper and MuTect) on the same set of genomic data from 133 acute myeloid leukemia (AML) patients, sequenced inside the Cancer Genome Atlas project, gave discrepant results. We subsequently tested these 2 variant-calling pip...

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Vydáno v:Blood
Hlavní autoři: Bodini, Margherita, Ronchini, Chiara, Giacò, Luciano, Russo, Anna, Melloni, Giorgio E. M., Luzi, Lucilla, Sardella, Domenico, Volorio, Sara, Hasan, Syed K., Ottone, Tiziana, Lavorgna, Serena, Lo-Coco, Francesco, Candoni, Anna, Fanin, Renato, Toffoletti, Eleonora, Iacobucci, Ilaria, Martinelli, Giovanni, Cignetti, Alessandro, Tarella, Corrado, Bernard, Loris, Pelicci, Pier Giuseppe, Riva, Laura
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304104/
https://ncbi.nlm.nih.gov/pubmed/25499761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-576157
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