The hidden genomic landscape of acute myeloid leukemia: subclonal structure revealed by undetected mutations

The analyses carried out using 2 different bioinformatics pipelines (SomaticSniper and MuTect) on the same set of genomic data from 133 acute myeloid leukemia (AML) patients, sequenced inside the Cancer Genome Atlas project, gave discrepant results. We subsequently tested these 2 variant-calling pip...

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Publicado no:Blood
Main Authors: Bodini, Margherita, Ronchini, Chiara, Giacò, Luciano, Russo, Anna, Melloni, Giorgio E. M., Luzi, Lucilla, Sardella, Domenico, Volorio, Sara, Hasan, Syed K., Ottone, Tiziana, Lavorgna, Serena, Lo-Coco, Francesco, Candoni, Anna, Fanin, Renato, Toffoletti, Eleonora, Iacobucci, Ilaria, Martinelli, Giovanni, Cignetti, Alessandro, Tarella, Corrado, Bernard, Loris, Pelicci, Pier Giuseppe, Riva, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304104/
https://ncbi.nlm.nih.gov/pubmed/25499761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-576157
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