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Poliovirus-induced inhibition of polypeptide initiation in vitro on native polyribosomes.

The inhibition of HeLa cell protein synthesis by poliovirus was studied by examining initiation in vitro on endogenous host polyribosomes. At an early stage, before major viral RNA replication and protein synthesis begins, the initiation of translation on cellular mRNA is strongly inhibited. Fractio...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kaufmann, Y, Goldstein, E, Penman, S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430401/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/180525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.6.1834
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