N-Glycosylation of cholera toxin B subunit in Nicotiana benthamiana: impacts on host stress response, production yield and vaccine potential

Plant-based transient overexpression systems enable rapid and scalable production of subunit vaccines. Previously, we have shown that cholera toxin B subunit (CTB), an oral cholera vaccine antigen, is N-glycosylated upon expression in transgenic Nicotiana benthamiana. Here, we found that overexpress...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hamorsky, Krystal Teasley, Kouokam, J. Calvin, Jurkiewicz, Jessica M., Nelson, Bailey, Moore, Lauren J., Husk, Adam S., Kajiura, Hiroyuki, Fujiyama, Kazuhito, Matoba, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303877/
https://ncbi.nlm.nih.gov/pubmed/25614217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08003
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