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Shiga Toxin 2-Induced Endoplasmic Reticulum Stress Is Minimized by Activated Protein C but Does Not Correlate with Lethal Kidney Injury

Enterohemorrhagic Escherichia coli produce ribotoxic Shiga toxins (Stx), which are responsible for kidney injury and development of hemolytic uremic syndrome. The endoplasmic reticulum (ER) stress response is hypothesized to induce apoptosis contributing to organ injury; however, this process has be...

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Bibliografiska uppgifter
I publikationen:Toxins (Basel)
Huvudupphovsmän: Parello, Caitlin S. L., Mayer, Chad L., Lee, Benjamin C., Motomochi, Amanda, Kurosawa, Shinichiro, Stearns-Kurosawa, Deborah J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303821/
https://ncbi.nlm.nih.gov/pubmed/25609181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7010170
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