Pro-Coagulant Endothelial Dysfunction Results from EHEC Shiga Toxins and Host Damage-Associated Molecular Patterns

Hemolytic uremic syndrome (HUS) from enterohemorrhagic Escherichia coli infection is a leading cause of kidney failure in otherwise healthy U.S. children. The bacterial Shiga toxins (Stx) induce the characteristic coagulopathy of HUS, but the damage to toxin-receptor expressing cells and organ injur...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mayer, Chad L., Parello, Caitlin S. L., Lee, Benjamin C., Itagaki, Kiyoshi, Kurosawa, Shinichiro, Stearns-Kurosawa, Deborah J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387861/
https://ncbi.nlm.nih.gov/pubmed/25904918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00155
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