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Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF

Pigment Epithelium Derived Factor (PEDF) is a secreted factor that has broad biological activities. It was first identified as a neurotrophic factor and later as the most potent natural antiangiogenic factor, a stem cell niche factor, and an inhibitor of cancer cell growth. Numerous animal models de...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Cheng, Guo, Zhong, Ming, Kawaguchi, Riki, Kassai, Miki, Al-Ubaidi, Muayyad, Deng, Jun, Ter-Stepanian, Mariam, Sun, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303762/
https://ncbi.nlm.nih.gov/pubmed/25535841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05401
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