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Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF
Pigment Epithelium Derived Factor (PEDF) is a secreted factor that has broad biological activities. It was first identified as a neurotrophic factor and later as the most potent natural antiangiogenic factor, a stem cell niche factor, and an inhibitor of cancer cell growth. Numerous animal models de...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303762/ https://ncbi.nlm.nih.gov/pubmed/25535841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05401 |
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