Crystal Structure of LGR4-Rspo1 Complex: INSIGHTS INTO THE DIVERGENT MECHANISMS OF LIGAND RECOGNITION BY LEUCINE-RICH REPEAT G-PROTEIN-COUPLED RECEPTORS (LGRs)

Leucine-rich repeat G-protein-coupled receptors (LGRs) are a unique class of G-protein-coupled receptors characterized by a large extracellular domain to recognize ligands and regulate many important developmental processes. Among the three groups of LGRs, group B members (LGR4–6) recognize R-spondi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Xu, Jin-Gen, Huang, Chunfeng, Yang, Zhengfeng, Jin, Mengmeng, Fu, Panhan, Zhang, Ni, Luo, Jian, Li, Dali, Liu, Mingyao, Zhou, Yan, Zhu, Yongqun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303694/
https://ncbi.nlm.nih.gov/pubmed/25480784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.599134
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