In Vivo Kinetics of Formate Metabolism in Folate-deficient and Folate-replete Rats

It is now established that the mitochondrial production of formate is a major process in the endogenous generation of folate-linked one-carbon groups. We have developed an in vivo approach involving the constant infusion of [(13)C]formate until isotopic steady state is attained to measure the rate o...

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發表在:J Biol Chem
Main Authors: Morrow, Gregory P., MacMillan, Luke, Lamarre, Simon G., Young, Sara K., MacFarlane, Amanda J., Brosnan, Margaret E., Brosnan, John T.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2015
主題:
Metabolism
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303675/
https://ncbi.nlm.nih.gov/pubmed/25480787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.600718
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