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The Short Stature Homeobox 2 (Shox2)-bone Morphogenetic Protein (BMP) Pathway Regulates Dorsal Mesenchymal Protrusion Development and Its Temporary Function as a Pacemaker during Cardiogenesis

The atrioventricular (AV) junction plays a critical role in chamber septation and transmission of cardiac conduction pulses. It consists of structures that develop from embryonic dorsal mesenchymal protrusion (DMP) and the embryonic AV canal. Despite extensive studies on AV junction development, the...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Sun, Cheng, Yu, Diankun, Ye, Wenduo, Liu, Chao, Gu, Shuping, Sinsheimer, Nathan R., Song, Zhongchen, Li, Xihai, Chen, Chun, Song, Yingnan, Wang, Shusheng, Schrader, Laura, Chen, YiPing
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303656/
https://ncbi.nlm.nih.gov/pubmed/25488669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619007
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