The Short Stature Homeobox 2 (Shox2)-bone Morphogenetic Protein (BMP) Pathway Regulates Dorsal Mesenchymal Protrusion Development and Its Temporary Function as a Pacemaker during Cardiogenesis

The atrioventricular (AV) junction plays a critical role in chamber septation and transmission of cardiac conduction pulses. It consists of structures that develop from embryonic dorsal mesenchymal protrusion (DMP) and the embryonic AV canal. Despite extensive studies on AV junction development, the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sun, Cheng, Yu, Diankun, Ye, Wenduo, Liu, Chao, Gu, Shuping, Sinsheimer, Nathan R., Song, Zhongchen, Li, Xihai, Chen, Chun, Song, Yingnan, Wang, Shusheng, Schrader, Laura, Chen, YiPing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303656/
https://ncbi.nlm.nih.gov/pubmed/25488669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619007
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