Clinical significance of tryptophan metabolism in the non-tumoral hemisphere in patients with malignant glioma

Alpha-(11)C-methyl-L-tryptophan positron emission tomography (AMT-PET) allows evaluation of brain serotonin synthesis and can also track upregulation of the immunosuppressive kynurenine pathway in tumor tissue. Increased AMT uptake is a hallmark of World Health Organization grade III–IV gliomas. Our...

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Publicado en:J Nucl Med
Autores principales: Kamson, David O., Lee, Tiffany J., Varadarajan, Kaushik, Robinette, Natasha L., Muzik, Otto, Chakraborty, Pulak K., Snyder, Michael, Barger, Geoffrey R., Mittal, Sandeep, Juhász, Csaba
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303620/
https://ncbi.nlm.nih.gov/pubmed/25189339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.114.141002
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