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Clinical significance of tryptophan metabolism in the non-tumoral hemisphere in patients with malignant glioma
Alpha-(11)C-methyl-L-tryptophan positron emission tomography (AMT-PET) allows evaluation of brain serotonin synthesis and can also track upregulation of the immunosuppressive kynurenine pathway in tumor tissue. Increased AMT uptake is a hallmark of World Health Organization grade III–IV gliomas. Our...
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| Publicado no: | J Nucl Med |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303620/ https://ncbi.nlm.nih.gov/pubmed/25189339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.114.141002 |
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