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Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

Intracellular ISG15 is an interferon (IFN)-α/β-inducible ubiquitin-like modifier which can covalently bind other proteins in a process called ISGylation; it is an effector of IFN-α/β-dependent antiviral immunity in mice(1–4). We previously published a study describing humans with inherited ISG15 def...

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מידע ביבליוגרפי
הוצא לאור ב:Nature
Main Authors: Zhang, Xianqin, Bogunovic, Dusan, Payelle-Brogard, Béatrice, Francois-Newton, Véronique, Speer, Scott D., Yuan, Chao, Volpi, Stefano, Li, Zhi, Sanal, Ozden, Mansouri, Davood, Tezcan, Ilhan, Rice, Gillian I., Chen, Chunyuan, Mansouri, Nahal, Alireza Mahdaviani, Seyed, Itan, Yuval, Boisson, Bertrand, Okada, Satoshi, Zeng, Lu, Wang, Xing, Jiang, Hui, Liu, Wenqiang, Han, Tiantian, Liu, Delin, Ma, Tao, Wang, Bo, Liu, Mugen, Liu, Jing-Yu, Wang, Qing K., Yalnizoglu, Dilek, Radoshevich, Lilliana, Uzé, Gilles, Gros, Philippe, Rozenberg, Flore, Zhang, Shen-Ying, Jouanguy, Emmanuelle, Bustamante, Jacinta, Garcìa-Sastre, Adolfo, Abel, Laurent, Lebon, Pierre, Notarangelo, Luigi D., Crow, Yanick J., Boisson-Dupuis, Stèphanie, Casanova, Jean-Laurent, Pellegrini, Sandra
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303590/
https://ncbi.nlm.nih.gov/pubmed/25307056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13801
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