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Unraveling the contributions of hydrogen-bonding interactions to the activity of native and non-native ligands in the quorum-sensing receptor LasR

Quorum sensing (QS) via the synthesis and detection of N-acyl L-homoserine lactone (AHL) signals regulates important pathogenic and mutualistic phenotypes in many bacteria. Over the past two decades, the development of non-native molecules that modulate this cell-cell signaling process has become an...

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Publicat a:Org Biomol Chem
Autors principals: Gerdt, Joseph P., McInnis, Christine E., Schell, Trevor L., Blackwell, Helen E.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303524/
https://ncbi.nlm.nih.gov/pubmed/25474181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob02252a
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