Chronic Passive Venous Congestion drives Hepatic Fibrogenesis via Sinusoidal Thrombosis and Mechanical Forces

Chronic passive hepatic congestion (congestive hepatopathy) leads to hepatic fibrosis; however the mechanisms involved in this process are not well understood. We developed a murine experimental model of congestive hepatopathy through partial ligation of the inferior vena cava (pIVCL). C57BL/6 and t...

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Pubblicato in:Hepatology
Autori principali: Simonetto, Douglas A, Yang, Hui-yin, Yin, Meng, de Assuncao, Thiago M, Kwon, Jung Hee, Hilsher, Moira, Pan, Shuchong, Yang, Liu, Bi, Yan, Beyder, Arthur, Cao, Sheng, Simari, Robert D, Ehman, Richard, Kamath, Patrick S, Shah, Vijay H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303520/
https://ncbi.nlm.nih.gov/pubmed/25142214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27387
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