Alpha-methyl ornithine, a potent competitive inhibitor of ornithine decarboxylase, blocks proliferation of rat hepatoma cells in culture.

A biphasic increase of putrescine concentration occurs in rat hepatoma tissue culture cells induced to proliferate. DL-alpha-Methyl ornithine, a competitive inhibitor of ornithine decarboxylase ( L-ornithine carboxylyase, EC 4.1.1.7) of hepatoma tissue culture cells, blocks the usual increases of pu...

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Bibliografiske detaljer
Main Authors: Mamont, P S, Böhlen, P, McCann, P P, Bey, P, Schuber, F, Tardif, C
Format: Artigo
Sprog:Inglês
Udgivet: 1976
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC430352/
https://ncbi.nlm.nih.gov/pubmed/1064034
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