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Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives
The inflammasome is a molecular platform formed by activation of an innate immune pattern recognition receptor seed, such as NLRP3. Once activated, NLRP3 recruits the adapter ASC (apoptosis-related speck-like protein containing a caspase recruitment domain), which in turn recruits procaspase-1. Proc...
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| Publicado en: | J Inflamm Res |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Dove Medical Press
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303395/ https://ncbi.nlm.nih.gov/pubmed/25653548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S51250 |
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